Research Design Service: East Midlands
National Institute for Health Research
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Research for Patient Benefit (RfPB) Tier 3 Funding review published

  Created on Tuesday, 02 May 2017. Posted in Funding

In competition 26 RfPB introduced a high risk funding tiers (Tier 3), this report identifies what has been currently funded via tier 3. Tier 3 funds projects that are higher risk and further away from patient benefit, the report additionally looks at the pathways the studies take to achieve patient benefit.  

  • Tier 1 (up to £350k) for research that has a clear and close trajectory to patient benefit, such as a definitive trial.
  • Tier 2 (up to £250k) for research proposals which are feasibility studies.
  • Tier 3 (up to £150k) for research which is on a pathway to patient benefit yet further from it

To date 21 projects have been funded under tier 3 accounting for 22% of all RfPB funded projects.

The funded projects fall into the following research types:

  • 3 systematic reviews
  • 7 developing and refining interventions
  • 1 meta-analysis
  • 1 realist synthesis
  • 1 economic evaluation
  • 6 secondary data analysis (including developing predictive models and needs assessments)
  • 2 diagnostic accuracy studies

Covering four types of research topics and designs:

  1. Therapeutic – concerned with developing and evaluating interventions to improve patient benefit
  2. Diagnostic – concerned with ensuring patients are appropriately classified to receive the above intervention
  3. Needs assessment – concerned with assessing the needs (usually of interventions) in a particular patient population
  4. Evidence synthesis.