Research Design Service: East Midlands

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Core outcome set - response to COVID-19

  Created on Friday, 01 May 2020. Posted in Priorities | Methods

Many clinical trials and systematic reviews are already underway, or will begin shortly, to strengthen the evidence base for the COVID-19 response. Core outcome sets (COS), showing the outcomes that should be measured and reported in these studies, will ensure that this evidence base will contain, as a minimum, the key information needed by decision makers about the effects of interventions.

COMET core outcome sets for trials and systematic reviews

Don't use James Lind Alliance Priority Setting as a tick box exercise

  Created on Thursday, 12 Sep 2019. Posted in Priorities

Citing the James Lind Alliance Priority Setting (JLA PS) as a reason why the research is important is a good way to justify your research question, however you need to do more that just say that JLA identified it as a priority!

In one or two sentences explain how the JLA PS resulted in the research question being posed. Provide numbers of people involved in the process of setting the priority, where it ranked and what the reasons were for setting it as a priority. Most importantly remember to say what difference answering that uncertainty will make to the NHS and patients.


Complex health and care needs in older people

  Created on Tuesday, 06 Feb 2018. Posted in Priorities

The NIHR has an on-going Highlight Notice is ‘Complex Health and Care Needs in Older People’.

The NIHR welcomes all relevant applications, and particularly those addressing the key themes identified at a stakeholder workshop:

  • Frailty,
  • Transitions in care, service delivery and models of care,
  • Medicines management/polypharmacy,
  • Promoting healthy ageing/preventing ill health,
  • Patient-centred decision making.

Researchers interested in this area should watch this useful video from Professors Chris Whitty, Bruce Guthrie and Tom Walley on the priorities that need to be addressed. 

Ongoing interest in previous research themes!

  Created on Monday, 18 Jan 2016. Posted in Funding | Priorities

Previous NIHR Themed Calls covered a range of topics, such as antimicrobial resistance and dementia. Even though the specific themed calls have closed, the NIHR continues to be interested in receiving applications in any of these areas. Applications can be made to any of the NIHR's funding programmes as part of their usual researcher-led workstreams. 
See list of previous NIHR Themed Calls.

‘The BIG Challenge’ puts spotlight on NIHR obesity research

  Created on Wednesday, 13 Jan 2016. Posted in Priorities | News Items

THE BIG Challenge

The NIHR CRN has launched ‘The BIG Challenge’ splash site dedicated to obesity research.

NIHR is currently supporting research into the condition across 43 obesity-related studies. The site highlights progress in tackling obesity as a result of NIHR studies, and includes patient and researcher case studies, stories and video’s about their experience in obesity research through four selected studies.


Top 10 priorities for research on mild-moderate hearing loss

  Created on Monday, 21 Sep 2015. Posted in Priorities

  1. What adverse effects are associated with not treating mild to moderate hearing loss in adults?
  2. Does the early fitting of hearing aid(s) result in increased patient benefit and/or improved cost-effectiveness of the service?
  3. Does the early fitting of hearing aids slow the rate of cognitive decline?
  4. What are the reasons for low hearing aid uptake, use and adherence?
  5. Can new technologies replace hearing aids?
  6. Can stem cell therapy offer a cure for mild to moderate hearing loss in adults?
  7. Does early identification, diagnosis and treatment of mild to moderate hearing loss prevent further deterioration of hearing?
  8. Could new developments to digital hearing aids offer improved speech perception in noisy environments?
  9. How realistic are hearing tests for assessing the everyday hearing abilities of adults with mild to moderate hearing loss?
  10. Could the use of real-world sounds to help program hearing aids in clinic (rather than tones or beeps) improve hearing aid effectiveness?

This list is the culmination of the work of a James Lind Alliance Priority Setting Partnership and will be sent to commissioners, funders and policy makers.